SAFETY AND EFFICACY OF PALBOCICLIB AND RADIATION THERAPY IN PATIENTS WITH METASTATIC BREAST CANCER: INITIAL RESULTS OF A NOVEL COMBINATION

Safety and Efficacy of Palbociclib and Radiation Therapy in Patients With Metastatic Breast Cancer: Initial Results of a Novel Combination

Purpose: Palbociclib is a selective cyclin-dependent kinase 4/6 inhibitor approved for metastatic ER+/HER2- breast cancer.Preclinical evidence suggests a possible synergistic effect of palbociclib when combined with radiation therapy (RT); however, the toxicity of this pairing is unknown.We report preliminary results on the use of this combination.

read more


A Global Law Perspective of the WTO

This note attempts to map the relevance of global law advocacy for the WTO.In this regard, it understands global att nighthawk hotspot law as an attempt to describe a growing decrease of the regulatory State and an ensuing increase of private rule-making.Global law intends to generate new thinking about global governance and its patterns of influen

read more